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Human cardiac catheterization was introduced by Werner Forssman in
1929.  Ignoring his department chief, and tying his assistant to an
operating table to prevent his interference, he placed a uretheral
catheter into a vein in his arm, advanced it to the right atrium [of
his heart], and walked upstairs to the x-ray department where he took
the confirmatory x-ray film.  In 1956, Dr. Forssman was awarded the
Nobel Prize.